EBF
EBF
EBF
European
Bioanalysis
Forum


EBF vzw is the registered non-profit organisation of the European Bioanalysis Forum

In this link you can find a chronological overview of the EBF publications. Full versions of the publications can be found on the websites of the respective publishers. In view of the copyright agreements, EBF will not provide reprints of the publications in below list. Please note that all of our recommendation papers are available free of charge

  1. Co-medication and interference testing in bioanalysis– Feedback from EBF discussions and frecommendations how to comply with regulatory requirements,
    Marcel de Zwart, Berthold Lausecker, Susanne Globig, Daniel Neddermann, Bruno Le Bras,  Alberto Guenzi, Stephen White, Marianne Scheel-Fjording and Philip Timmerman
    Bioanalys is, 2015, in press
  2. Development of a Generic Laboratory Manual for Biological Sample Logistics in Clinical Pharmacokinetic Studies
    Richard Abbott, Rebecca Sleigh, Jeff Long, Carina Ekstrom, Bernd Matthes and José Groenboom-Nieuwenhuijzen Clinical Investigation, 2015, in press
  3. Tiered approach into practice – scientific validation for chromatography-based assays: a recommendation from the European Bioanalysis Forum,
    Philip Timmerman, Stephen White, Stuart Mc Dougall, Morten A. Kall, John Smeraglia, Marianne Scheel Fjording and Magnus Knutsson
    Bioanalysis, Vol. 7, No. 18, Pages 2387-2398.
  4. Scientific or regulated validation: a tiered approach? Meeting report from a joint EBF/DVDMDG workshop
    Philip Timmerman, Steve Lowes, Stuart McDougall, Irina Colligon, Joy Miksic, Swapan Chowdhury,  Steve White, Anne-Françoise Aubry, Rand Jenkins and Christopher Kemper
    Bioanalysis (2015) 7(14), 1703–1710  (joint EBF/DV-DMDG publication)
  5. An alternative design for long-term stability testing of large molecules – an EBF evaluation
    Susanne Pihl, Lene Andersen, Katharina Bruzelius, Christine Schiebl, Michaela Golob
    Bioanalysis, 2014, in press
  6. European Bioanalysis Forum – Reflection on bioanalytical assay requirements used to support Liquid Microsampling
    Stephen White, Glen Hawthorne, Lieve Dillen, Neil Spooner, Karen Woods, Timothy Sangster, Zoe Cobb and Philip Timmerman
    Bioanalysis, 2014, Vol. 6, No. 19, Pages 2581-2586
  7. Stabilization of clinical samples collected for quantitative bioanalysis – a reflection from the European Bioanalysis Forum
    Martijn. J. Hilhorst, Peter van Amsterdam, Katja Heinig, Elke Zwanziger, Richard Abbott.
    Bioanalysis, 2014, in press
  8. European Bioanalysis Forum – Recommendation on Dealing with Haemolysed and Hyper-lipidemic Matrices
    Benno Ingelse, Begona Barroso, Nicholas Gray, Verena Jakob-Rodamer, Clare Kingsley, Corinna Sykora, Petra Vinck , Martina Wein and Stephen White
    Bioanalysis, 2014, Vol. 6, No. 23, Pages 3113-3120
  9. European Bioanalysis Forum – Recommendation on Dealing with Internal Standard Variability
    Stephen White, Neil Adcock, Walid Elbast, Jim Hillier, Magnus Knutsson, Berthold Lausecker, Jeff Long, Stuart McDougall, Fabrice Salavert, Timothy Sangster, Tom Verhaeghe, Peter van Amsterdam
    Bioanalysis, 2014, Vol. 6, No. 20, Pages 2767-2774.
  10. Feedback from the European Bioanalysis Forum Workshop: Taking tiered approach to the next level.
    Philip Timmerman, Stephen White, Magnus Knutsson, Morten Anders Kall, Marianne Scheel Fjording, John Smeraglia and Stuart McDougall.
    Bioanalysis, 2014, Vol. 6, No. 19, Pages 2593-2598.
  11. European Bioanalysis Forum continued plans to support liquid microsampling.
    Philip Timmerman, Steve White, Zoe Cobb, Karen Woods, Ronald de Vries, Neil Spooner, Timothy Sangster, Lieve Dillen, Glen Hawthorne.
    Bioanalysis, 2014, Vol. 6, No. 14, Pages 1897-1900.
  12. Recommendations from the European Bioanalysis Forum on method establishment for tissue homogenates.
    Philip Timmerman, Nathalie Mokrzycki, Pascal Delrat, Marc De Meulder, Eva Erbach, Irene Lentheric, Morna McIntosh, Pawel Dzygiel.
    Bioanalysis, 2014,Vol. 6, No. 12, Pages 1647-1656.
  13. Feedback from a European Bioanalysis Forum survey on bioanalysis of drugs in tissues.
    Nathalie Mokrzycki, Pascal Delrat, Marc De Meulder, Eva Erbach, Irene Lenthéric, Morna McIntosh, Pawel Dzygiel, Philip Timmerman.
    Bioanalysis, 2014, Vol. 6, No. 12, Pages 1617-1626.
  14. How the bioanalytical scientist plays a key role in interdisciplinary project teams in the development of biotherapeutics – a reflection of the European Bioanalysis Forum.
    Sherri Dudal, Roland F Staack, Daniela Stoellner, Marianne Scheel Fjording, Eva Vieser, Marie-Hélène Pascual, Margarete Brudny-Kloeppel, Michaela Golob.
    Bioanalysis, 2014, Vol. 6, No. 10, Pages 1339-1348.
  15. EBF recommendation for stability testing of anti-drug antibodies; lessons learned from anti-vaccine antibody stability studies.
    Susanne Pihl, Lydia Michaut, Jenny Hendriks, Ralf Loebbert, Janka Ryding, Martin Nemansky, Laurent Vermet, Arjen Companjen.
    Bioanalysis, 2014, Vol. 6, No. 10, Pages 1409-1413.
  16. Conference Report: AAPS and US FDA Crystal City V meeting on Quantitative Bioanalytical Method Validation and Implementation: feedback from the EBF.
    John Smeraglia, Stuart McDougall, Karen Elsby, Arjen Companjen, Stephen White, Michaela Golob, Margarete Brudny-Kloeppel, Peter van Amsterdam, Philip Timmerman.
    Bioanalysis, 2014, Vol. 6, No. 6, Pages 729-732.
  17. Bioanalysis for plasma protein binding studies in drug discovery and drug development: views and recommendations of the European Bioanalysis Forum.
    Brigitte Buscher, Sirpa Laakso, Hermann Mascher, Klaus Pusecker, Mira Doig, Lieve Dillen, Winfried Wagner-Redeker, Thomas Pfeifer, Pascal Delrat, Philip Timmerman.
    Bioanalysis, 2014, Vol. 6, No. 5, Pages 673-682.
  18. Update of the EBF recommendation for the use of DBS in regulated bioanalysis integrating the conclusions from the EBF DBS-microsampling consortium
    Philip Timmerman, Steve White, Zoe Cobb, Ronald de Vries, Elizabeth Thomas, Ben van Baar.
    Bioanalysis, 2013, Vol. 5, No. 17, Pages 2129-2136.
  19. In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium
    Zoe Cobb, Ronald de Vries, Neil Spooner, Stephen Williams, Ludovicus Staelens, Mira Doig, Rebecca Broadhurst, Matthew Barfield, Nico van de Merbel, Bernhard Schmid, Christoph Siethoff, Jordi Ortiz, Elwin Verheij, Ben van Baar, Steve White, Philip Timmerman
    Bioanalysis, 2013, Vol. 5, No. 17, Pages 2161-2169.
  20. IS addition in bioanalysis of DBS: results from the EBF DBS-microsampling consortium
    Ben LM van Baar, Tom Verhaeghe, Olivier Heudi, Morten Rohde, Simon Wood, Jaap Wieling, Ronald de Vries, Steve White, Zoe Cobb, Philip Timmerman
    Bioanalysis, 2013, Vol. 5, No. 17, Pages 2137-2145.
  21. The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium
    Ronald de Vries, Matthew Barfield, Nico van de Merbel, Bernhard Schmid, Christoph Siethoff, Jordi Ortiz, Elwin Verheij, Ben van Baar, Zoe Cobb, Steve White, Philip Timmerman
    Bioanalysis, 2013, Vol. 5, No. 17, Pages 2147-2160.
  22. LC–MS/MS of large molecules in a regulated bioanalytical environment – which acceptance criteria to apply?
    Magnus Knutsson, Ronald Schmidt, Philip Timmerman
    Bioanalysis, 2013, Vol. 5, No. 18, Pages 2211-2214
  23. The European Bioanalysis Forum community’s evaluation, interpretation and implementation of the European Medicines Agency guideline on Bioanalytical Method Validation
    Peter van Amsterdam, Arjen Companjen, Margarete Brudny-Kloeppel, Michaela Golob, Silke Luedtke, Philip Timmerman
    Bioanalysis, 2013, Vol. 5, No. 6, Pages 645-659.
  24. Managing scientific, technical and regulatory innovation in regulated bioanalysis: a discussion paper from the European Bioanalysis Forum
    Philip Timmerman, Neil Henderson, John Smeraglia, Hans Mulder, Benno Ingelse, Margarete Brudny-Kloeppel, Arjen Companjen
    Bioanalysis, 2013, Vol. 5, No. 2, Pages 139-145
  25. Conference Report: The 3rd EBF Focus Meeting: ‘Hatching’ – emerging technologies approaching the regulated bioanalysis laboratory
    Jessica Dijksman, Neil Henderson, Benno Ingelse, Hans Mulder, John Smeraglia, Philip Timmerman, Margarete Brudny-Kloeppel, Arjen Companjen, Peter van Amsterdam
    Bioanalysis, Dec 2012, Vol. 4, No. 23, Pages 2769-2774.
  26. European Bioanalysis Forum recommendation: scientific validation of quantification by accelerator mass spectrometry
    David Higton, Graeme Young, Philip Timmerman, Richard Abbott, Magnus Knutsson, Leif D Svensson
    Bioanalysis, Nov 2012, Vol. 4, No. 22, Pages 2669-2679
  27. European Bioanalysis Forum recommendation on biomarker bioanalysis published in Bioanalysis
    Philip Timmerman
    Biomarkers Med. (2012) 6(4) Page 509
  28. Updates from the EBF DBS–microsampling consortium
    Philip Timmerman, Steve White, Zoe Cobb, Ronald de Vries, Elisabeth Thomas, Ben van Baar, Christopher Smith, Dieter Zimmer, Pascal Delrat, John Smeraglia, Silke Lüdtke
    Bioanalysis, Aug 2012, Vol. 4, No. 16, Pages 1969-1970.
  29. European Bioanalysis Forum recommendation on method establishment and bioanalysis of biomarkers in support of drug development
    Philip Timmerman, Christian Herling, Daniela Stoellner, Birgit Jaitner, Susanne Pihl, Karen Elsby, Neil Henderson, Begona Barroso, Stephanie Fischmann, Arjen Companjen, Amanda Versteilen, Stewart Bates, Clare Kingsley, Ulrich Kunz
    Bioanalysis, Aug 2012, Vol. 4, No. 15, Pages 1883-1894.
  30. Conference report from the European Bioanalysis Forum Open Meeting: Less is More – Defining modern Bioanalysis
    Jessica Dijksman, Philip Timmerman, Richard Abbott,  Begona Barroso, Margarete Brudny Kloeppel, Arjen Companjen, Michaela Golob, Ben Gordon,  Christian Herling, Magnus Knutsson, Silke Luedtke,  Birgitte Buur Rasmussen, Daniela Stoellner, Eva Vieser, Graeme Young, Peter van Amsterdam
    Bioanalysis (2012) 4(6) 633-642
  31. Conference report from the European Bioanalysis Forum Open Meeting – ‘Large meets Small’ on connecting the bioanalytical community around peptide and protein bioanalysis with LC-MS(/MS)
    Philip Timmerman, Berthold Lausecker, Begona Barossa, Peter van Amsterdam, Silke Luedtke and Jessica Dijksman
    Bioanalysis (2012) 4(6) 627-631
  32. Anticoagulant counter ion impact on bioanalytical LC-MS/MS assays: results from discussions and experiments within the European Bioanalysis Forum
    Carl Johan Sennbro, Magnus Knutsson, Peter van Amsterdam, Philip Timmerman
    Bioanalysis, November 2011, Vol. 3, No. 21, Pages 2393-2399
  33. Anticoagulant counter ion impact on bioanalytical LC-MS/MS assay performance: additional validation required?
    Carl Johan Sennbro, Magnus Knutsson, Philip Timmerman, Peter van Amsterdam
    Bioanalysis, November 2011, Vol. 3, No. 21, Pages 2389-2391.
  34. EBF and dried blood spots: from recommendations to potential resolution
    Philip Timmerman, Steve White, Susanne Globig, Silke Lüdtke, Leonarda Brunet, Christopher Smith, John Smeraglia
    Bioanalysis, Aug 2011, Vol. 3, No. 16, Pages 1787-1789.
  35. EBF recommendation on the validation of bioanalytical methods for dried blood spots
    Philip Timmerman, Steve White, Susanne Globig, Silke Lüdtke, Leonarda Brunet, John Smeraglia
    Bioanalysis, Jul 2011, Vol. 3, No. 14, Pages 1567-1575.
  36. Workshop/Conference Report on EMA Draft Guideline on Validation of Bioanalytical Methods
    Henning Blume, Erich Brendel, Margarete Brudny-Klöppel, Sylvia Grebe, Berthold Lausecker, Gabriele Rohde, Christoph Siethoff
    European J. of Pharmaceutical Sciences 42(2011) 300-305
  37. Blood stability testing: European Bioanalysis Forum view on current challenges for regulated bioanalysis
    Achim Freisleben, Margarete Brudny-Klöppel, Hans Mulder, Ronald de Vries, Marcel de Zwart, Philip Timmerman
    Bioanalysis, Jun 2011, Vol. 3, No. 12, Pages 1333-1336
  38. Conference Report 3rd Open EBF Symposium: From challenges to solutions
    Richard W Abbott, Ben Gordon, Peter van Amsterdam, Berthold Lausecker, Margarete Brudny-Kloeppel, John Smeraglia, Fernando Romero, Susanne Globig, Michaela Golob, Magnus Knutsson, Christian Herling, Eva Vieser, Philip Timmerman
    Bioanalysis, April 2011, Vol. 3, No. 8, Pages 833-838
  39. Conference Report EBF 1st Focus Meeting: Connecting strategies on dried blood spots
    Richard Abbott, John Smeraglia, Stephen White, Silke Luedtke, Leonarda Brunet, Elizabeth Thomas, Susanne Globig, Philip Timmerman
    Bioanalysis, Nov 2010, Vol. 2, No. 11, Pages 1809-1816
  40. Global Bioanalysis Consortium – Working towards a functional globally acceptable and harmonized guideline on bioanalytical method validation
    Peter van Amsterdam, Mark Arnold, Surendra Bansal, Douglas Fast, Fabio Garofolo, Philip Timmerman, Eric Woolf
    Bioanalysis 2(11), 1801-1803 (2010)
  41. Best practices in a tiered approach to metabolite quantification: views and recommendations of the European Bioanalysis Forum
    Philip Timmerman, Morten Anders Kall, Ben Gordon, Sirpa Laakso, Achim Freisleben, Richard Hucker
    Bioanalysis, July 2010, Vol. 2, No. 7, Pages 1185-1194
  42. Towards harmonized regulations for bioanalysis: moving forward!
    Peter van Amsterdam, Berthold Lausecker, Silke Luedtke, Philip Timmerman, Margarete Brudny-Kloeppel
    Bioanalysis 2010 2:4, 689-691
  43. Request for Global Harmonization of the Guidance for Bioanalytical Method Validation and Sample Analysis
    Philip Timmerman, Steve Lowes, Douglas M Fast, Fabio Garofolo
    Bioanalysis 2010 2:4, 683-683
  44. Conference Report 2nd Open EBF Symposium: The Broadening Scope of Validation: Towards Best Practices in the World of Bioanalysis
    Richard W. Abbott
    Bioanalysis 2010, 1:4, 703-708
  45. Succesvol eerste EBF symposium
    Peter van Amsterdam
    Laboratorium Magazine Nr 2, 2009
  46. Konferenz Report: European Bioanalysis Forum 1st Open Symposium “Burning Issues in Bioanalysis”, 01-02 December 2008, Hilton Hotel, Barcelona
    Richard W. Abbott and Margarete Brudny-Kloeppel
    Nachrichten aus der Chemie (DE)
  47. Incurred sample reproducibility: views and recommendations by the European Bioanalysis Forum
    Philip Timmerman, Silke Luedtke, Peter van Amsterdam, Margarete Brudny-Kloeppel, Berthold Lausecker
    Bioanalysis 2009 1:6, 1049-1056
  48. European Bioanalysis Forum and the way forward towards harmonized regulations
    Berthold Lausecker, Peter van Amsterdam, Margarete Brudny-Kloeppel, Silke Luedtke, Philip Timmerman
    Bioanalysis 2009 1:5, 873-875
  49. Conference Report 1st Open EBF Symposium: European Bioanalysis Forum
    Richard W Abbott, Margarete Brudny-Kloeppel
    Bioanalysis 2009 1:2, 273-276